Criteria for the Identification of Chikungunya Infection

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Clinical criteria

• acute onset of fever >38.5°C
• severe arthralgia/arthritis not explained by other medical conditions

Epidemiological criteria

• Residing or having visited epidemic areas
• having reported transmission within 15 days prior to the onset of symptoms

Laboratory Criteria: at least one of the following tests in the acute phase:

• Virus isolation by Cell Culture
• Presence of viral RNA by real Time RT-PCR (Within 5 days of onset of Illness)
• Presence of viral specific IgM antibody in single serum sample collected within 5 to 28 days of onset Fever
• Four-fold Rise of IgG antibody in samples collected at least three weeks apart (1^st sample after 7 days )