Laboratory Diagnosis

exp date isn't null, but text field is

Preferred Specimen:

1) Blood or Serum

2) CSF (if neurological features present)

Routine Laboratory Investigations

  • CBC
    • Leucopenia (Decreased WBC)
    • Thrombocytopenia: rare
    • ESR: Usually Elevated
  • C-Reactive Protein: Increased during the Acute Phase and may remain elevated for a week
  • SGPT: Elevated

Specific Laboratory Investigations: at least one of the following tests in the acute phase:

  • Virus isolation by Cell Culture
  • Presence of viral RNA by real Time RT-PCR (Within 5 days of onset of Illness)
  • Presence of viral specific IgM antibody in single serum sample collected within 5 to 28 days of onset Fever
  • Four-fold Rise of IgG antibody in samples collected at least three weeks apart (1st sample after 7 days )

N.B.:

  1. Diagnostic validity of currently available ICT kit for the detection of IgM and IgG for Chikungunya virus is very poor.
  2. RT-PCR for Chikungunya is performed only at IEDCR.