Treatment of serious complications

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  • Bleeding disorders with blood components- platelet transfusions in case of bleeding with platelet counts of less than 50,000 cells per cu mm., fresh frozen plasma, or Vitamin K injections if prothrombin time INR is more than 2.
  • Hypotension with fluids/ inotropics, acute renal failure with dialysis, contractures and deformities with physiotherapy/surgery,
  • Patients with myo-pericarditis or meningoencephalitis may require intensive care with regular monitoring, inotropic support, ventilation etc.
  • Anti-neuralgic drugs (Amitryptyline, Carbamazepine, Gabapentin, and Pregabalin) may be used in standard doses in disturbing neuropathies.
  • Use hydroxychloroquine 200 mg orally once daily or chloroquin phosphate 300 mg orally per day for a period of four weeks in cases where arthralgia is refractory to other drugs.
  • Hyperpigmentation and papular eruptions may be managed with Zinc oxide cream and/or Calamine lotion