2. Vivax Malaria (VM)

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Objectives of Treatment of VM:

The clinical objectives of treating vivax malaria are to cure the infection as rapidly as possible and to prevent relapse. The public health objectives of treatment are to prevent onward transmission of the infection to others and to prevent the emergence and spread of resistance to antimalarial drugs. If BSE and /or RDT is positive for P. vivax then it will be labeled as VM.

Treatment of Vivax Malaria (VM):

Chloroquine 3 days+ Primaquine 14 days (CQ3+PQ14)

Dose Schedule:

❖ Chloroquine (CQ):

  • 1st day: 10 mg/kg (4 tabs for adult)
  • 2nd day: 10 mg/kg (4 tabs for adult)
  • 3rd day: 5 mg/kg (2 tabs for adult)

❖ Primaquine (PQ):

  • To be given along with choloroquine from first day.
  • 0.25 mg/kg for 14 days

Precaution:

G6PD deficient patient can develop severe haemolysis after getting primaquine, which can manifest by anaemia, jaundice, yellow colour of urine, vomiting and haemoglobinuria. If any one of these develops, then the drug should he stopped and patient should be hospitalized for blood transfusion and supportive management.

Patient receiving 14 days' Primaquine should have follow up information (Pharmacovigillance).