5.11 Treatment outcome of TB patients

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All TB patients need to be provided with an outcome at the end of the treatment and this needs to be duly recorded for each TB patient. The following table shows the possible outcomes for TB patients.

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⁸ “Bacteriological response” refers to bacteriological conversion with no reversion. • “bacteriological conversion” describes a situation in a patient with bacteriologically confirmed TB where at least two consecutive cultures (for DR-TB and DS-TB) or smears (for DS-TB only), taken on different occasions at least 7 days apart, are negative. • “bacteriological reversion” describes a situation where at least two consecutive cultures (for DR-TB and DS-TB) or smears (for DS-TB only), taken on different occasions at least 7 days apart, are positive either after the bacteriological conversion or in patients without bacteriological confirmation of TB.

⁹ Reasons for the change include: • no clinical response and/or no bacteriological response (see note ‘8’); • adverse drug reactions; or • evidence of additional drug resistance to medicines in the regimen