5.2 Basic Principles of TB treatment

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The goal of treatment is to achieve a relapse free cure by effectively killing all TB bacilli in the infected patient. To achieve this, the basic principles of effective TB treatment are:

  • Prescribing an appropriate combination of drugs
  • Administering the drugs for the required duration (several months).
  • Ensuring correct dosage to achieve the optimum therapeutic effect.

Treatment approaches

5.2.1 Standardized treatment or regimen

All patients in a defined group should receive the same regimen. Different groups might receive a different regimen. For example:

  • All patients with a strain susceptible to first-line drugs should receive the same standard treatment regimen for 6 months, (may be extended up to 12 months, depending on the site of involvement).
  • Patients who fail to respond to the first-line anti-TB drugs, will be tested with Gene Xpert and whenever possible both 1st line and 2nd line DST (LPA, Liquid culture & DST) will be done and patient will be managed as per DR TB guidelines.