9.2 Target Groups for DR TB and First-line DST
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If available, rapid DST will be offered to all presumptive TB cases before starting TB treatment. In case not available, then the following groups will be prioritised for DST (Presumptive DR TB):
- All Previously Treated (Retreatment) cases at diagnosis
- Failure of Cat-1 and retreatment regimen
- Relapse
- Treatment after loss to follow-up
- Non-Converter (remain positive at month 2 of treatment follow-up)
- Close contacts of DR TB patients with symptoms
- HIV Infected person, with /without TB S/S
- Bacteriologically negative Pulmonary TB turning smear positive at 2 months or extra pulmonary TB patients showing clinical deterioration or no signs of clinical improvement, despite treatment as per NTP guidelines.
Ensure proper history taking and quality lab performance including follow up sputum examination for identification of presumptive DR TB as per above groups.