Syphilis

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Syphilis

Description

Most common congenital infection in our setting. Two thirds of affected infants have no clinical signs of congenital syphilis

Signs and Symptoms

• Persistent snuffles
• Erythematous rash, which may be macular or popular and affects the palms and soles
• Osteoporosis and periostitis on x-ray

Investigations

• TPHA
• RPR/VDRL

Treatment

Symptomatic baby	10-day course Benzyl Penicillin IV 50, 000 U/kg/dose twice a day
Asymptomatic baby + partially or untreated mother	Single dose Benzathine Penicillin (IM) 50, 000 U/kg